Article
ABC transporters as phenotypic markers and functional regulators of stem cells.
Stem cells (Dayton, Ohio) - 1 Jan 2002
Bunting Kevin D
Abstract excerpt
Characterization of molecules with tightly controlled expression patterns during differentiation represents an approach to understanding regulation of hematopoietic stem cell commitment. The multidrug resistance-1 (MDR1) gene product, P-glycoprotein, and the breast cancer resistance protein (BCRP) are expressed differentially during hematopoiesis, with the highest levels in primitive bone marrow stem cell...
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