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Article

Comparison of three methods for obtaining principal components from family data in genetic analysis of complex disease.

Genetic epidemiology - 1 Jan 2001

Moser K L, Jedrey C M, Conti D, Schick J H, Gray-McGuire C, Nath S K, Daley D, Olson J M

Abstract excerpt

Three multivariate techniques used to derive principal components (PCs) from family data were compared for their ability to model family data and power to detect linkage. Using the simulated data from Genetic Analysis Workshop 12, the five quantitative traits were first adjusted for age, sex, and environmental factors 1 and 2. Then, standard PCs, PCs obtained from between-family covariance, and PCs obtained from...

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PMID: 11793768
DOI: 10.1002/gepi.2001.21.s1.s726

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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