Article
Exploring pleiotropy using principal components.
BMC genetics - 31 Dec 2003
Bensen Jeannette T, Lange Leslie A, Langefeld Carl D, Chang Bao-Li, Bleecker Eugene R, Meyers Deborah A, Xu Jianfeng
Abstract excerpt
A standard multivariate principal components (PCs) method was utilized to identify clusters of variables that may be controlled by a common gene or genes (pleiotropy). Heritability estimates were obtained and linkage analyses performed on six individual traits (total cholesterol (Chol), high and...
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