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Article

Comparison of Heritability Estimation and Linkage Analysis for Multiple Traits Using Principal Component Analyses.

Genetic epidemiology - 1 Apr 2016

Liang Jingjing, Cade Brian E, Wang Heming, Chen Han, Gleason Kevin J, Larkin Emma K, Saxena Richa, Lin Xihong, Redline Susan, Zhu Xiaofeng

Abstract excerpt

A disease trait often can be characterized by multiple phenotypic measurements that can provide complementary information on disease etiology, physiology, or clinical manifestations. Given that multiple phenotypes may be correlated and reflect common underlying genetic mechanisms, the use of multivariate analysis of multiple traits may improve statistical power to detect genes and variants underlying complex...

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PMID: 27027516
DOI: 10.1002/gepi.21957
PMCID: PMC5083066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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