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Article

Quantitative trait linkage analysis of the liability underlying a common oligogenic disease.

Genetic epidemiology - 1 Jan 2001

Maher B S, Vanyukov M M, Cooper M E, Neiwswanger K, Marazita M L

Abstract excerpt

We utilized pedigree discriminant and factor analytic approaches to combine multivariate phenotypic information into a single liability phenotype in the isolate and general populations. We applied two-stage relative-pair quantitative trait linkage analysis to detect genetic contributions to variation in the resulting liability phenotypes. Linkage analysis revealed several regions of suggestive linkage in both the...

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Identifiers

PMID: 11793767
DOI: 10.1002/gepi.2001.21.s1.s720

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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