Clustering of pedigrees using marker allele frequencies: impact on linkage analysis.

Abstract excerpt

Ethnicity may form the basis for locus heterogeneity at certain susceptibility loci for complex diseases. Classification of pedigrees into ethnic groups is usually based upon self-report, but this may not be sensitive or specific. We investigated whether it is possible to cluster families from an admixed population using pedigree-specific marker allele frequencies. We used 323 autosomal microsatellite markers...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Asthma
• Share to Black or African American
• Share to Black People