Article
Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies.
American journal of human genetics - 1 Feb 2005
Tang Hua, Quertermous Tom, Rodriguez Beatriz, Kardia Sharon L R, Zhu Xiaofeng, Brown Andrew, Pankow James S, Province Michael A, Hunt Steven C, Boerwinkle Eric, Schork Nicholas J, Risch Neil J
Abstract excerpt
We have analyzed genetic data for 326 microsatellite markers that were typed uniformly in a large multiethnic population-based sample of individuals as part of a study of the genetics of hypertension (Family Blood Pressure Program). Subjects identified themselves as belonging to one of four major racial/ethnic groups (white, African American, East Asian, and Hispanic) and were recruited from 15 different...
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