Article
Constraint structure analysis of gene expression.
Functional & integrative genomics - 1 Nov 2000
Rifkin S A, Atteson K, Kim J
Abstract excerpt
A microarray experiment gives a snapshot of the state of an organism in terms of the relative abundances of its mRNA transcripts, locating the organism at a point in a high dimensional state space where each axis represents the relative expression level of a single gene. Multiple experiments generate a cloud of points in this gene expression space. We present a geometric approach to analyzing the covariational...
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