Article
Spectral biclustering of microarray data: coclustering genes and conditions.
Genome research - 1 Apr 2003
Kluger Yuval, Basri Ronen, Chang Joseph T, Gerstein Mark
Abstract excerpt
Global analyses of RNA expression levels are useful for classifying genes and overall phenotypes. Often these classification problems are linked, and one wants to find "marker genes" that are differentially expressed in particular sets of "conditions." We have developed a method that simultaneously clusters genes and conditions, finding distinctive "checkerboard" patterns in matrices of gene expression data, if...
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