Genetic variation at the adipsin locus and response to long-term overfeeding.

doi:10.1038/sj.ejcn.1601644

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Article

Genetic variation at the adipsin locus and response to long-term overfeeding.

European journal of clinical nutrition - 1 Sept 2003

Ukkola O, Chagnon M, Tremblay A, Bouchard C

Abstract excerpt

OBJECTIVES: The role of adipsin and adipsin Hinc II polymorphisms on the metabolic and body composition changes in response to overfeeding was studied. SUBJECTS: A total of 12 pairs of male monozygotic twins ate a 4.2 MJ/day energy surplus, 6 days a week, during a period of 100 days. RESULTS: The preoverfeeding plasma adipsin concentration correlated positively with the change in CT-measured abdominal total and...

Topics

Abdomen
Adipose Tissue
Adult
Body Mass Index
Complement Factor D
Female
Genetic Variation
Humans
Insulin
Leptin
Lipids
Male
Overnutrition
Serine Endopeptidases
Skinfold Thickness
Statistics, Nonparametric
Tomography, X-Ray Computed
Twins, Monozygotic

Source

Open in PubMed

Identifiers

PMID: 12947425
DOI: 10.1038/sj.ejcn.1601644

Provenance

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