Article
Beta-2 adrenergic receptor variants are associated with subcutaneous fat accumulation in response to long-term overfeeding.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Nov 2001
Ukkola O, Tremblay A, Bouchard C
Abstract excerpt
OBJECTIVE: The effects of alpha-2A (A2A)-, beta-2 (B2)- and beta-3 (B3)-adrenergic receptor (ADR) gene polymorphisms on adiposity, fat distribution and plasma insulin and leptin changes in response to long-term overfeeding were explored. METHODS: Twenty four men (mean (+/-s.d.) age 21+/-2 y) who constituted 12 pairs of identical twins ate a 4.2 MJ/day energy surplus, 6 days a week, for a period of 100 days. Total...
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