Article
The role of iron and haemochromatosis gene mutations in the progression of liver disease in chronic hepatitis C.
Gut - 1 Feb 2002
Thorburn D, Curry G, Spooner R, Spence E, Oien K, Halls D, Fox R, McCruden E A B, MacSween R N M, Mills P R
Abstract excerpt
BACKGROUND: Chronic hepatitis C virus (HCV) infection is frequently associated with elevated markers of iron stores. Recessively inherited mutations in the HFE gene are responsible for iron accumulation in most cases of hereditary haemochromatosis and may have a role in HCV infection. They may also be associated with progressive liver fibrosis although this remains controversial. AIMS: To assess the prevalence of...
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