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Are Haemochromatosis Mutations Related to the Severity of Liver Disease in Hepatitis C Virus Infection?

1 Jan 1999

Abstract excerpt

It has been proposed that iron overload may adversely affect liver disease outcome. The recent identification of 2 mutations in the HFE gene related to hereditary haemochromatosis (Cys282Tyr and His63Asp) provided an opportunity to test whether they are associated with hepatic iron accumulation and the activity and severity of liver disease in hepatitis C virus (HCV) infection. We investigated the prevalence of...

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PMID: 10692680
DOI: 10.1159/000040991

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