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Article

Active site structure and stereospecificity of Escherichia coli pyridoxine-5'-phosphate oxidase.

Journal of molecular biology - 18 Jan 2002

di Salvo Martino L, Ko Tzu-Ping, Musayev Faik N, Raboni Samanta, Schirch Verne, Safo Martin K

Abstract excerpt

Pyridoxine-5'-phosphate oxidase catalyzes the oxidation of either the C4' alcohol group or amino group of the two substrates pyridoxine 5'-phosphate and pyridoxamine 5'-phosphate to an aldehyde, forming pyridoxal 5'-phosphate. A hydrogen atom is removed from C4' during the oxidation and a pair of electrons is transferred to tightly bound FMN. A new crystal form of the enzyme in complex with pyridoxal 5'-phosphate...

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Identifiers

PMID: 11786019
DOI: 10.1006/jmbi.2001.5254

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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