Two distinct mechanisms for differential positioning of gene expression borders involving the Drosophila gap protein giant.

doi:10.1242/dev.125.19.3765

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Article

Two distinct mechanisms for differential positioning of gene expression borders involving the Drosophila gap protein giant.

Development (Cambridge, England) - 1 Oct 1998

Wu X, Vakani R, Small S

Abstract excerpt

We have combined genetic experiments and a targeted misexpression approach to examine the role of the gap gene giant (gt) in patterning anterior regions of the Drosophila embryo. Our results suggest that gt functions in the repression of three target genes, the gap genes Krüppel (Kr) and hunchbac...

Topics

Amino Acid Sequence
Animals
Bacterial Proteins
Base Sequence
Body Patterning
DNA
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Gene Expression Regulation, Developmental
Gene Targeting
Genes, Insect
Homeodomain Proteins
In Situ Hybridization
Insect Proteins
Kruppel-Like Transcription Factors
Mutation
RNA, Messenger

Source

Open in PubMed

Identifiers

PMID: 9729485
DOI: 10.1242/dev.125.19.3765

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9729485-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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