Article
Two distinct mechanisms for differential positioning of gene expression borders involving the Drosophila gap protein giant.
Development (Cambridge, England) - 1 Oct 1998
Wu X, Vakani R, Small S
Abstract excerpt
We have combined genetic experiments and a targeted misexpression approach to examine the role of the gap gene giant (gt) in patterning anterior regions of the Drosophila embryo. Our results suggest that gt functions in the repression of three target genes, the gap genes Krüppel (Kr) and hunchback (hb), and the pair-rule gene even-skipped (eve). The anterior border of Kr, which lies 4-5 nucleus diameters...
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