Article
In vivo interactions of the Drosophila Hairy and Runt transcriptional repressors with target promoters.
The EMBO journal - 16 Dec 1996
Jiménez G, Pinchin S M, Ish-Horowicz D
Abstract excerpt
The Hairy and Runt pair-rule proteins regulate Drosophila segmentation by repressing transcription. To explore the ability of these proteins to function as promoter-bound regulators in vivo, we examined the effects of Hairy and Runt derivatives containing heterologous transcriptional activation d...
Topics
- Animals
- Basic Helix-Loop-Helix Transcription Factors
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Female
- Gene Expression
- Genes, Lethal
- Insect Hormones
- Insect Proteins
- Male
- Nuclear Proteins
- Phenotype
- Promoter Regions, Genetic
- Repressor Proteins
- Transcription Factors