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Article

Plasma levels of endothelial protein C receptor respond to anticoagulant treatment.

Blood - 15 Jan 2002

Stearns-Kurosawa Deborah J, Swindle Kandice, D'Angelo Armando, Della Valle Patrizia, Fattorini Annalisa, Caron Nathalie, Grimaux Marc, Woodhams Barry, Kurosawa Shinichiro

Abstract excerpt

The endothelial protein C receptor (EPCR) facilitates protein C activation and plays a protective role in the response to Escherichia coli-mediated sepsis in primates. Previously, a soluble form of EPCR (sEPCR) in human plasma was characterized, and several studies indicated that generation of sEPCR is regulated by inflammatory mediators, including thrombin-mediated up-regulation of surface metalloproteolytic...

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PMID: 11781234
DOI: 10.1182/blood.v99.2.526

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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