Article
Mice lacking the gene for inducible or endothelial nitric oxide are resistant to sporocyst induced Sarcocystis neurona infections.
Veterinary parasitology - 4 Feb 2002
Rosypal Alexa C, Lindsay David S, Duncan Robert, Ahmed S Ansar, Zajac Anne M, Dubey J P
Abstract excerpt
Equine protozoal myeloencephalitis (EPM) is a neurologic syndrome in horses from the Americas and is usually caused by infection with the apicomplexan parasite, Sarcocystis neurona. Little is known about the role of immunobiological mediators to this parasite. Nitric oxide (NO) is important in resistance to many intracellular parasites. We, therefore, investigated the role of inducible and endothelial NO in...
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