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Article

CD8+ CTLs are essential for protective immunity against Encephalitozoon cuniculi infection.

Journal of immunology (Baltimore, Md. : 1950) - 15 May 1999

Khan I A, Schwartzman J D, Kasper L H, Moretto M

Abstract excerpt

Encephalitozoon cuniculi is a protozoan parasite that has been implicated recently as a cause of opportunistic infection in immunocompromised individuals. Protective immunity in the normal host is T cell-dependent. In the present study, the role of individual T cell subtypes in immunity against this parasite has been studied using gene knockout mice. Whereas CD4-/- animals resolved the infection, mice lacking...

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Share to CD8 Antigens
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10229850

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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