Article
Susceptibility and resistance to monocytic ehrlichiosis in the mouse.
Annals of the New York Academy of Sciences - 1 Dec 2005
Winslow Gary M, Bitsaktsis Constantine, Yager Eric
Abstract excerpt
To address the role of cellular immunity during ehrlichia infection, we have utilized a model of monocytic ehrlichiosis that results from infection of mice by Ixodes ovatus ehrlichia (IOE). Although ehrlichiosis in humans is largely a disease of immunocompromised individuals, the use of the IOE model has allowed us to identify factors required for host defense in normal mice. Using a low-dose infection C57BL/6...
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