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Article

Visual disorders associated with omeprazole and their relation to CYP2C19 polymorphism.

Pharmacogenetics - 1 Jan 2002

Lutz Markus, Schwab Matthias, Griese Ernst-Ulrich, Marx Claudia, Müller-Oerlinghausen Bruno, Schönhöfer Peter S, Meisner Christoph, Gleiter Christoph H, Eichelbaum Michel, Mörike Klaus

Abstract excerpt

Risk factors for patients developing visual disturbances in association with proton pump inhibitors are unknown. As omeprazole is substantially metabolized by polymorphic CYP2C19, we retrospectively identified and genotyped patients who experienced this adverse reaction. Among 29 patients, we found two poor metabolizers (PMs) of CYP2C19. The PM genotype does not appear to be a risk factor for...

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Identifiers

PMID: 11773867
DOI: 10.1097/00008571-200201000-00010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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