Article
[URE3] and [PSI] are prions of yeast and evidence for new fungal prions.
Current issues in molecular biology - 1 Apr 2000
Masison D C, Edskes H K, Maddelein M L, Taylor K L, Wickner R B
Abstract excerpt
[URE3] and [PSI] are two non-Mendelian genetic elements discovered over 25 years ago and never assigned to a nucleic acid replicon. Their genetic properties led us to propose that they are prions, altered self-propagating forms of Ure2p and Sup35p, respectively, that cannot properly carry out the normal functions of these proteins. Ure2p is partially protease-resistant in [URE3] strains and Sup35p is aggregated...
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