Article

Large-scale phenotyping and comparative genomics reveal genetic features of <i>Listeria</i> persistence in epithelial cells

2025-06-23

Abstract excerpt

During infection in epithelial cells, after invading the cytosol, multiplying, and spreading, Listeria monocytogenes ( Lm ) ceases to produce ActA and becomes trapped in Listeria -containing vacuoles (LisCVs). These persistence acidic vacuoles harbor bacterial subpopulations that resist to stress in a metabolically dormant state. Although LisCVs have been proposed as a hallmark of Lm persistence in epithelial...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0f7fd446-e6a3-5025-bf73-58b72aa2daad
DOI: 10.1101/2025.06.23.661024

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Large-scale phenotyping and comparative genomics reveal genetic features of <i>Listeria</i> persistence in epithelial cellsDOI 10.1101/2025.06.23.661024Read

Large-scale phenotyping and comparative genomics reveal genetic features of Listeria persistence in epithelial cells.Semantic proximity Read

<i>E. coli</i> associated with Crohn’s disease exhibit distinct strategies to colonize macrophagesSemantic proximity Read

Comparative genomics and transcriptomics of lineages I, II, and III strains of Listeria monocytogenes.Semantic proximity Read

Recent advances in understanding Listeria monocytogenes infection: the importance of subcellular and physiological contextSemantic proximity Read

<i>Listeria monocytogenes</i> gene essentiality under laboratory conditions and during macrophage infectionSemantic proximity Read

From vacuole to cytosol – Disruptive invasion triggers cytosolic release of <i>Salmonella</i> Paratyphi A and subsequent cytosolic motility favors evasion of xenophagySemantic proximity Read

Comparative genomics of the bacterial genus Listeria: Genome evolution is characterized by limited gene acquisition and limited gene loss.Semantic proximity Read

Long-term persistence of diverse clones shapes the transmission landscape of invasive Listeria monocytogenes.Semantic proximity Read

Clinical isolates of <i>Enterobacter</i> species can persist in human macrophages without bacterial replication and minimal cellular cytotoxicitySemantic proximity Read

A genome-wide screen in <i>ex vivo</i> gallbladders identifies <i>Listeria monocytogenes</i> factors required for virulence <i>in vivo</i>Semantic proximity Read

Disentangling the impacts of abiotic and biotic environmental factors and dispersal dynamics on the pangenome fluidity of bacterial pathogensSemantic proximity Read

Whole genome-based population biology and epidemiological surveillance of Listeria monocytogenes.Semantic proximity Read