Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impaired striatal dopamine output of homozygous Wfs1 mutant mice in response to [K+] challenge.

Journal of physiology and biochemistry - 1 Mar 2011

Matto Vallo, Terasmaa Anton, Vasar Eero, Kõks Sulev

Abstract excerpt

Loss of function of the Wfs1 gene causes Wolfram syndrome, a rare multisystem degenerative disorder. Mutant mice with targeted Wfs1 gene disruption (Wfs1 KO) display morphological and behavioral impairments that are not well understood. The present study aimed to investigate the striatal dopamine output of wild-type, heterozygous, and homozygous Wfs1 null-mutant mice using in vivo microdialysis technique. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Corpus Striatum
Share to Dopamine
Share to Homozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Proteins

Share to Mice, Transgenic

Share to Microdialysis

Share to Potassium Chloride

Share to Wolfram Syndrome

Source

Identifiers

PMID: 20972658
DOI: 10.1007/s13105-010-0048-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impaired striatal dopamine output of homozygous Wfs1 mutant mice in response to [K+] challenge.PMID 20972658Read ↗

Wolfram syndrome 1 regulates sleep in dopamine receptor neurons by modulating calcium homeostasis.Semantic proximity Read ↗

In vitro release of endogenous dopamine from the striatum of the weaver mutant mouse.Semantic proximity Read ↗

Striatal dopamine output is compromised within +/- BDNF mice.Semantic proximity Read ↗

Parkin Knockdown Modulates Dopamine Release in the Central Complex, but Not the Mushroom Body Heel, of Aging DrosophilaSemantic proximity Read ↗

Distribution of dopamine, its metabolites, and D1 and D2 receptors in heterozygous and homozygous weaver mutant mice.Semantic proximity Read ↗

Extracellular matrix protein anosmin-1 overexpression regulates dopaminergic phenotype in the CNS and the PNS with no pathogenic consequences in MPTP model of Parkinson’s diseaseSemantic proximity Read ↗

A <i>Drosophila</i> Wolfram Syndrome 1 (WFS1) homologue synergises with the intracellular Ca <sup>2+</sup> release channel, IP <sub>3</sub> R to affect mitochondrial morphology and functionSemantic proximity Read ↗

Dysbindin-1 Mutation Alters Prefrontal Cortex Extracellular Glutamate and Dopamine In Vivo.Semantic proximity Read ↗

Drosophila vesicular monoamine transporter mutants can adapt to reduced or eliminated vesicular stores of dopamine and serotonin.Semantic proximity Read ↗

Multimodal Detection of Dopamine by Sniffer Cells Expressing Genetically Encoded Fluorescence SensorsSemantic proximity Read ↗

A mouse model of the schizophrenia-associated 1q21.1 microdeletion syndrome exhibits altered mesolimbic dopamine transmission.Semantic proximity Read ↗

Cell-intrinsic effects of TorsinA(ΔE) disrupt dopamine release in a mouse model of TOR1A dystonia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.