Article
Control of Epstein–Barr virus reactivation by activated CD40 and viral latent membrane protein 1
18 Dec 2001
Abstract excerpt
In humans, Epstein-Barr virus (EBV) establishes a persistent latent infection in peripheral resting B lymphocytes. Virus reactivation is highly restricted. Whereas in healthy humans the infection usually is benign, immunocompromised patients show an increased risk for EBV-associated malignancies, accompanied by an increase in virus replication and in the number of virus-infected cells. To search for viral and...
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