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Article

A-type K+ current mediated by the Kv4 channel regulates the generation of action potential in developing cerebellar granule cells.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jun 2000

Shibata R, Nakahira K, Shibasaki K, Wakazono Y, Imoto K, Ikenaka K

Abstract excerpt

During neuronal differentiation and maturation, electrical excitability is essential for proper gene expression and the formation of synapses. The expression of ion channels is crucial for this process; in particular, voltage-gated K(+) channels function as the key determinants of membrane excitability. Previously, we reported that the A-type K(+) current (I(A)) and Kv4.2 K(+) channel subunit expression increased...

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Identifiers

PMID: 10818150
PMCID: PMC6772624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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