Article
Differential association of the codon 72 p53 and GSTM1 polymorphisms on histological subtype of non-small cell lung carcinoma.
Cancer research - 15 Dec 2001
Liu G, Miller D P, Zhou W, Thurston S W, Fan R, Xu L L, Lynch T J, Wain J C, Su L, Christiani D C
Abstract excerpt
Traditionally, non-small cell lung cancer (NSCLC) has been evaluated as a unique entity in genotyping studies. However, recent biological data suggest that different NSCLC subtypes, specifically adenocarcinomas (AC) and squamous cell carcinomas (SCC), differentially alter cancer behavior. Several studies have associated a p53 polymorphism at codon 72 with NSCLC susceptibility. This study investigated whether...
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