Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Combinations of the variant genotypes of GSTP1, GSTM1, and p53 are associated with an increased lung cancer risk.

Cancer research - 15 May 2002

Miller David P, Liu Geoffrey, De Vivo Immaculata, Lynch Thomas J, Wain John C, Su Li, Christiani David C

Abstract excerpt

GSTP1 and GSTM1 are genes involved in Phase II metabolism, whereas p53 is a tumor suppressor gene. Individually, functional polymorphisms of these genes have been studied as risk factors for lung cancer. Small sample sizes have hindered the detection of possible increases in risk associated with having two or more "at risk" polymorphisms of these three genes. In a large Caucasian population, we examined the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Genes, p53

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glutathione S-Transferase pi

Share to Glutathione Transferase

Share to Isoenzymes

Share to Lung Neoplasms

Share to Models, Genetic

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 12019159

Genes

GSTP1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Combinations of the variant genotypes of GSTP1, GSTM1, and p53 are associated with an increased lung cancer risk.PMID 12019159Read ↗

Combined genetic polymorphism and risk for development of lung cancer.Semantic proximity Read ↗

Differential association of the codon 72 p53 and GSTM1 polymorphisms on histological subtype of non-small cell lung carcinoma.Semantic proximity Read ↗

Combinations of glutathione S-transferase genotypes and risk of early-onset lung cancer in Caucasians and African Americans: a population-based study.Semantic proximity Read ↗

Combined effects of the p53 and p73 polymorphisms on lung cancer risk.Semantic proximity Read ↗

Glutathione-S-Transferase M1 and codon 72 p53 polymorphisms in a northwestern Mediterranean population and their relation to lung cancer susceptibility.Semantic proximity Read ↗

Germ line polymorphisms of p53 and CYP1A1 genes involved in human lung cancer.Semantic proximity Read ↗

The p53 codon 72 polymorphism and lung cancer risk.Semantic proximity Read ↗

Meta- and pooled analysis of GSTP1 polymorphism and lung cancer: a HuGE-GSEC review.Semantic proximity Read ↗

Combined effect of GSTM1, GSTT1 and GSTP1 polymorphisms on histological subtypes of lung cancer.Semantic proximity Read ↗

High susceptibility to lung cancer analyzed in terms of combined genotypes of P450IA1 and Mu-class glutathione S-transferase genes.Semantic proximity Read ↗

Genetic polymorphism of lysyl oxidase, glutathione S-transferase M1, glutathione-S-transferase T1, and glutathione S-transferase P1 genes as risk factors for lung cancer in Egyptian patients.Semantic proximity Read ↗

N-Methylpurine DNA Glycosylase and OGG1 DNA Repair Activities: Opposite Associations With Lung Cancer RiskSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.