Article
Combinations of the variant genotypes of GSTP1, GSTM1, and p53 are associated with an increased lung cancer risk.
Cancer research - 15 May 2002
Miller David P, Liu Geoffrey, De Vivo Immaculata, Lynch Thomas J, Wain John C, Su Li, Christiani David C
Abstract excerpt
GSTP1 and GSTM1 are genes involved in Phase II metabolism, whereas p53 is a tumor suppressor gene. Individually, functional polymorphisms of these genes have been studied as risk factors for lung cancer. Small sample sizes have hindered the detection of possible increases in risk associated with...
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