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Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts

7 Dec 2001

Abstract excerpt

Osteoblast development is a complex process involving the expression of specific growth factors and regulatory proteins that control cell proliferation, differentiation, and maturation. In this study, we used the rat mutation, osteopetrosis (op), to examine differences in skeletal gene expression between mutant op and normal littermates. Total RNA isolated from long bone and calvaria was used as a template for...

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PMID: 11746512
DOI: 10.1002/jcb.1259

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