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Article

Molecular determinants of high affinity binding to group III metabotropic glutamate receptors.

The Journal of biological chemistry - 1 Mar 2002

Rosemond Erica, Peltekova Vanya, Naples Mark, Thøgersen Henning, Hampson David R

Abstract excerpt

The amino-terminal domain containing the ligand binding site of the G protein-coupled metabotropic glutamate receptors (mGluRs) consists of two lobes that close upon agonist binding. In this study, we explored the ligand binding pocket of the Group III mGluR4 receptor subtype using site-directed...

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PMID: 11744707
DOI: 10.1074/jbc.M110476200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11744707-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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