Article
The role of Arg(78) in the metabotropic glutamate receptor mGlu(1) for agonist binding and selectivity.
European journal of pharmacology - 2 Jun 2000
Jensen A A, Sheppard P O, O'Hara P J, Krogsgaard-Larsen P, Bräuner-Osborne H
Abstract excerpt
The metabotropic glutamate receptors belong to family C of the G-protein coupled receptor superfamily. These receptors all possess large extracellular amino terminal domains, where agonist binding takes place. We have previously constructed a molecular model of the amino terminal domain of the mG...
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