Article
A sampling algorithm for segregation analysis.
Genetics, selection, evolution : GSE - 1 Jan 2000
Tier B, Henshall J
Abstract excerpt
Methods for detecting Quantitative Trait Loci (QTL) without markers have generally used iterative peeling algorithms for determining genotype probabilities. These algorithms have considerable shortcomings in complex pedigrees. A Monte Carlo Markov chain (MCMC) method which samples the pedigree of the whole population jointly is described. Simultaneous sampling of the pedigree was achieved by sampling descent...
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