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Article

Genome-wide Chromatin Mapping Defines AP2α in the Etiology of Craniofacial Disorders.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Mar 2015

Enkhmandakh Badam, Bayarsaihan Dashzeveg

Abstract excerpt

Objective : The aim of this study is to identify direct AP2α target genes implicated in craniofacial morphogenesis. Design : AP2α, a product of the TFAP2A gene, is a master regulator of neural crest differentiation and development. AP2α is expressed in ectoderm and in migrating cranial neural crest (NC) cells that provide patterning information during orofacial development and generate most of the skull bones and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24641171
DOI: 10.1597/13-151

Genes

MAFB
MSX1
TBX22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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