Article
Regulation of Hoxa2 in cranial neural crest cells involves members of the AP-2 family.
Development (Cambridge, England) - 1 Apr 1999
Maconochie M, Krishnamurthy R, Nonchev S, Meier P, Manzanares M, Mitchell P J, Krumlauf R
Abstract excerpt
Hoxa2 is expressed in cranial neural crest cells that migrate into the second branchial arch and is essential for proper patterning of neural-crest-derived structures in this region. We have used transgenic analysis to begin to address the regulatory mechanisms which underlie neural-crest-specific expression of Hoxa2. By performing a deletion analysis on an enhancer from the Hoxa2 gene that is capable of...
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