Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

research paper: Differential expression of <i>HDAC3, HDAC7</i> and <i>HDAC9</i> is associated with prognosis and survival in childhood acute lymphoblastic leukaemia

16 Jul 2010

Abstract excerpt

Altered expression of histone deacetylases (HDACs) is a common feature in several human malignancies and may represent an interesting target for cancer treatment, including haematological malignancies. We evaluated the mRNA gene expression profile of 12 HDAC genes by quantitative real-time polymerase chain reaction in 94 consecutive childhood acute lymphoblastic leukaemia (ALL) samples and its association with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Epigenetics and DNA Methylation
Share to Histone Deacetylase Inhibitors Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20636436
DOI: 10.1111/j.1365-2141.2010.08301.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

research paper: Differential expression of <i>HDAC3, HDAC7</i> and <i>HDAC9</i> is associated with prognosis and survival in childhood acute lymphoblastic leukaemiaPMID 20636436Read ↗

A Comprehensive Overview of Recent Advances in Epigenetics in Pediatric Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Targeting class I histone deacetylases in cancer therapySemantic proximity Read ↗

Epigenetic alterations in acute lymphoblastic leukemiaSemantic proximity Read ↗

HDAC3 inhibition as a therapeutic strategy in T-cell acute lymphoblastic leukemia via the TYK2-STAT1-BCL2 signaling pathwaySemantic proximity Read ↗

Role of HDACs in normal and malignant hematopoiesisSemantic proximity Read ↗

HDAC isoenzyme expression is deregulated in chronic lymphocytic leukemia B-cells and has a complex prognostic significanceSemantic proximity Read ↗

Histone deacetylase inhibitors: targeting epigenetic regulation in the treatment of acute leukemiaSemantic proximity Read ↗

Selective Inhibition of HDAC1 and HDAC2 as a Potential Therapeutic Option for B-ALLSemantic proximity Read ↗

Histone acetylation: novel target for the treatment of acute lymphoblastic leukemiaSemantic proximity Read ↗

Inhibition of histone deacetylases in cancer therapy: lessons from leukaemiaSemantic proximity Read ↗

Increased activity of histone deacetylases in childhood acute lymphoblastic leukaemia and acute myeloid leukaemia: support for histone deacetylase inhibitors as antileukaemic agentsSemantic proximity Read ↗

Comprehensive analysis of HDAC7 expression and its prognostic value in diffuse large B cell lymphomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.