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Article

Lymphoid apoptosis and myeloid hyperplasia in CCAAT displacement protein mutant mice.

Blood - 15 Dec 2001

Sinclair A M, Lee J A, Goldstein A, Xing D, Liu S, Ju R, Tucker P W, Neufeld E J, Scheuermann R H

Abstract excerpt

CCAAT displacement protein (cux/CDP) is an atypical homeodomain protein that represses expression of several developmentally regulated lymphoid and myeloid genes in vitro, including gp91-phox, immunoglobulin heavy chain, the T-cell receptor beta and gamma chains, and CD8. To determine how this activity affects cell development in vivo, a hypomorphic allele of cux/CDP was created by gene targeting. Homozygous...

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Source

Identifiers

PMID: 11739170
DOI: 10.1182/blood.v98.13.3658

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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