Hair defects and pup loss in mice with targeted deletion of the first cut repeat domain of the Cux/CDP homeoprotein gene.

doi:10.1006/dbio.1998.8950

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Article

Hair defects and pup loss in mice with targeted deletion of the first cut repeat domain of the Cux/CDP homeoprotein gene.

Developmental biology - 1 Aug 1998

Tufarelli C, Fujiwara Y, Zappulla D C, Neufeld E J

Abstract excerpt

CDP, a ubiquitous homeoprotein homologous to Drosophila cut, is implicated as a transcriptional repressor in several developmental systems. It contains four independent DNA binding domains: three "cut repeats" plus the homeodomain. The murine Cux/CDP gene spans more than 200 kb and is composed of...

Topics

Animals
Caseins
Chimera
DNA-Binding Proteins
Exons
Female
Gene Targeting
Hair
Homeodomain Proteins
Homozygote
Lactation
Mice
Mice, Mutant Strains
Milk
Mortality
Mutagenesis, Insertional
Mutation
Nuclear Proteins

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