Article
Allelic frequencies and patterns of single-nucleotide polymorphisms in candidate genes for asthma and atopy in Iceland.
American journal of respiratory and critical care medicine - 1 Dec 2001
Hakonarson H, Bjornsdottir U S, Ostermann E, Arnason T, Adalsteinsdottir A E, Halapi E, Shkolny D, Kristjansson K, Gudnadottir S A, Frigge M L, Gislason D, Gislason T, Kong A, Gulcher J, Stefansson K
Abstract excerpt
Numerous asthma and atopy loci have been reported in studies demonstrating associations of the asthma-related phenotypes atopy, elevated IgE levels, and bronchial hyperresponsiveness with alleles of microsatellite markers and single-nucleotide polymorphisms (SNPs) within specific cytokine/chemokine and IgE-regulating genes. Although the studies reporting these observations are compelling, most of them lack...
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