Article
Cytogenetic and molecular abnormalities in myelodysplastic syndrome.
Current molecular medicine - 1 Nov 2011
Nagoshi H, Horiike S, Kuroda J, Taniwaki M
Abstract excerpt
Myelodysplastic syndrome (MDS) is a heterogeneous group of clonal hematological disorders characterized by ineffective hematopoiesis which causes peripheral cytopenias and a risk of progression to acute myeloid leukemia. Although various forms of chromosomal abnormalities have been detected in approximately 50-60% of patients with de novo MDS and in up to 80% of patients with therapy-related MDS, their molecular...
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