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Article

The Drosophila maternal gene sésame is required for sperm chromatin remodeling at fertilization.

Chromosoma - 1 Nov 2001

Loppin B, Berger F, Couble P

Abstract excerpt

The spermatozoon features an extremely condensed and inactive nucleus. The unique sperm chromatin organization is acquired during the late stages of spermatid differentiation by the replacement of somatic histones with sperm-specific chromosomal proteins. At fertilization, the inactive sperm nucleus must be rapidly transformed into a DNA replication competent male pronucleus before the formation of the zygote....

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PMID: 11735001
DOI: 10.1007/s004120100161

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Drosophila maternal gene sésame is required for sperm chromatin remodeling at fertilization.PMID 11735001Read ↗

The maternal effect mutation sésame affects the formation of the male pronucleus in Drosophila melanogaster.Semantic proximity Read ↗

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Remodelling the paternal chromatin at fertilization in mammalsSemantic proximity Read ↗

Remodelling the paternal chromatin at fertilization in mammalsSemantic proximity Read ↗

Contribution of the paternal histone epigenome to the preimplantation embryoSemantic proximity Read ↗

Histone removal in sperm protects paternal chromosomes from premature division at fertilizationSemantic proximity Read ↗

The mouse meiotic mutation mei1 disrupts chromosome synapsis with sexually dimorphic consequences for meiotic progression.Semantic proximity Read ↗

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