Article
Longitudinal changes in physiological, radiological, and health status measurements in alpha(1)-antitrypsin deficiency and factors associated with decline.
American journal of respiratory and critical care medicine - 15 Nov 2001
Dowson L J, Guest P J, Stockley R A
Abstract excerpt
The FEV(1) declines rapidly in alpha(1)-antitrypsin deficiency (alpha(1)-ATD) but less is known about other measures of disease severity and the factors, other than smoking, that are associated with progression of emphysema. The natural history of alpha(1)-ATD was studied prospectively in 43 patients with the PiZ phenotype and emphysema at a single center over 2 yr. The mean +/- SE change in FEV(1) was -67 +/- 14...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.