Article
Prevalence and impact of bronchiectasis in alpha1-antitrypsin deficiency.
American journal of respiratory and critical care medicine - 15 Dec 2007
Parr David G, Guest Peter G, Reynolds John H, Dowson Lee J, Stockley Robert A
Abstract excerpt
RATIONALE: alpha(1)-Antitrypsin (AAT) deficiency is associated with increased risk of chronic obstructive pulmonary disease (COPD), in particular emphysema, but airway disease is less well described. OBJECTIVES: To assess the prevalence of airways disease in subjects with AAT deficiency and to identify the relationship between radiological airway abnormalities and clinical phenotype. METHODS: We characterized the...
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