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Article

Recent advances in α-1-antitrypsin deficiency-related lung disease.

Expert review of respiratory medicine - 1 Jun 2013

Brebner Judith A, Stockley Robert A

Abstract excerpt

α-1-antitrypsin deficiency (A1ATD) is an under-recognized hereditary disorder associated with the premature onset of chronic obstructive pulmonary disease. There is considerable heterogeneity in the phenotypic expression of lung disease in A1ATD and the pathophysiology is complex, involving the interaction of multiple pathways. Other genetic factors that may contribute to emphysema risk in A1AT-deficient...

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Identifiers

PMID: 23734645
DOI: 10.1586/ers.13.20

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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