Article
The novel plant homeodomain protein rhinoceros antagonizes Ras signaling in the Drosophila eye.
Genetics - 1 Dec 2003
Voas Matthew G, Rebay Ilaria
Abstract excerpt
The sequential specification of cell fates in the Drosophila eye requires repeated activation of the epidermal growth factor receptor (EGFR)/Ras/MAP kinase (MAPK) pathway. Equally important are the multiple layers of inhibitory regulation that prevent excessive or inappropriate signaling. Here we describe the molecular and genetic analysis of a previously uncharacterized gene, rhinoceros (rno), that we propose...
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