Article
[Elastase inhibitors].
Journal de la Societe de biologie - 1 Jan 2001
Reboud-Ravaux M
Abstract excerpt
The serine proteinase elastase is located in the azurophil granules of mature circulating polymorphonuclear neutrophils. This neutrophil elastase or NE is a potent non specific serine protease which plays a role as bactericidal agent and in the degradation of immune complexes by intraphagosomal processes. It promotes inflammation when the granule contents are secreted in the extracellular environment. In certain...
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