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Article

Polymorphisms in the vicinity of the hypocretin/orexin are not associated with human narcolepsy.

Neurology - 27 Nov 2001

Hungs M, Lin L, Okun M, Mignot E

Abstract excerpt

Human narcolepsy/cataplexy is associated with reduced hypocretin (orexin) transmission. A common preprophypocretin (HCRT) polymorphism (-909C/T) was identified and tested in 502 subjects (105 trio families, 80 Caucasian narcolepsy cases, and 107 Caucasian control subjects). This polymorphism was not associated with the disease. The promoter and 5' untranslated (5'URT) regions of the HCRT gene (-320 to +21 from...

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Source

Identifiers

PMID: 11723284
DOI: 10.1212/wnl.57.10.1893

Genes

HCRT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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