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Article

[Temperature-sensitive mutants of Japanese encephalitis virus, isolated from chronically infected cultures of suckling mouse brain cells].

Voprosy virusologii - 1 Jan 2000

Gavrilov V I, Deriabin P G, Loginova N V

Abstract excerpt

Reproduction of Japanese encephalitis virus isolated at various passage levels from chronically infected GMS-1-K33 cell cultures was maximum in chick embryo fibroblast cultures at a temperature of 28 degrees C. A temperature of 42 degrees C was found to be nonpermissive for the majority of variants and restrictive for the 20th passage virus. Some decline in titers was also observed at 37 degrees C. The ts mutants...

Topics

Animals
Brain
Cell Line
Chick Embryo
Encephalitis Virus, Japanese
Fibroblasts
Mice
Mutation
Temperature
Viral Plaque Assay
Virus Replication

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PMID: 1172327

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1172327-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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