Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Induction of alphavirus ts-mutations by N-methyl-N-nitro-N-nitrosoguanidine added to the replicating virus].

Voprosy virusologii - 1 Jan 2000

Shablinskaia L M, Tsilinskiĭ Ia Ia

Abstract excerpt

The possibility of producing ts mutants of Sindbis and eastern equine encephalomyelitis (EEE) virus by treatment of replicating virus with N-methyl-N-nitro-N-nitrosoguanidine was studied. N-methyl-N-nitro-N-nitrosoguanidine added in a concentration of 20 micrograms/ml to chick fibroblast cultures infected with Sindbis virus for 4 hours was shown to induce ts mutations in the virus. Under similar conditions no ts...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chick Embryo
Share to Methylnitronitrosoguanidine
Share to Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Sindbis Virus

Share to Virus Cultivation

Share to Virus Replication

Source

Identifiers

PMID: 6324493

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Induction of alphavirus ts-mutations by N-methyl-N-nitro-N-nitrosoguanidine added to the replicating virus].PMID 6324493Read ↗

[Ts mutants of the Eastern equine encephalomyelitis virus. Their generation, isolation and preliminary characterization].Semantic proximity Read ↗

[Preparation and characteristics of temperature-sensitive mutants of the Venezuelan equine encephalomyelitis virus].Semantic proximity Read ↗

[A comparative study of various genetic markers of eastern equine encephalomyelitis virus and its mutants induced by nitrous acid].Semantic proximity Read ↗

[Temperature-sensitive mutants of the Venezuelan equine encephalomyelitis virus studied in the complementation test].Semantic proximity Read ↗

[Production of temperature-sensitive mutants of vaccinia virus with the aid of nitrosomethylurea, and their preliminary characteristics].Semantic proximity Read ↗

[Mechanism of viral variability. Methylmethanesulfonate-induced mutation process in Western equine encephalomyelitis virus in cells with active and defective repair systems].Semantic proximity Read ↗

[Interaction of Venezuelan equine encephalitis virus ts-mutants with cells].Semantic proximity Read ↗

The association of the temperature-sensitive phenotype with viral attenuation in animals and humans: implications for the development and use of live virus vaccines.Semantic proximity Read ↗

[Role of temperature-sensitive mutants in the natural evolution of the influenza virus].Semantic proximity Read ↗

[Molecular biology characteristics of an attenuated mutant of the Eastern equine encephalomyelitis virus].Semantic proximity Read ↗

[Thermo-inactivation of viruses. 3. A comparative study of the t-r and t-s variants of Venezuelan equine encephalomyelitis virus].Semantic proximity Read ↗

[Influence of actinomycin D on the effectiveness of producing ts mutants of the Japanese encephalitis virus].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.