Article
[Temperature sensitive mutant of Herpes simplex virus type 1. II. Neurovirulence and latency].
Medycyna doswiadczalna i mikrobiologia - 1 Jan 2001
Litwińska B, Trzcińska A, Kańtoch M
Abstract excerpt
The course of acute infection of mice with ts mutant or the native strain DNA and the antigens of HSV in brain nerve cells were determined. Virus DNA was detected in brains of all mice in both animal groups while the virus antigens--only in cells of mice infected with the native strain. It can be suggested, therefore, that the ability of ts mutant to replicate in central nervous system of the infected mice is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.