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Article

Optimizing detection of QTLs retarding aging: choice of statistical model and animal requirements.

Mechanisms of ageing and development - 1 Jan 2002

Klebanov S, Harrison D E

Abstract excerpt

Quantitative trait locus (QTL) analysis makes no assumptions about the identity of genes involved in regulating aging. Moreover, it may be used as the first step in identifying such genes and, thus QTL analysis may be instrumental in formulating new hypotheses about aging. Genetic experiments, however, require hundreds to thousands of animals and are very expensive in mammals. Statistical power to detect...

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PMID: 11718807
DOI: 10.1016/s0047-6374(01)00340-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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